REDUCING COLONOSCOPIES IN PATIENTS WITHOUT SIGNIFICANT BOWEL DISEASE: THE RECEDE STUDY - PROTOCOL FOR A PROSPECTIVE DIAGNOSTIC ACCURACY STUDY

REducing Colonoscopies in patients without significant bowEl DiseasE: the RECEDE Study - protocol for a prospective diagnostic accuracy study

Introduction Demand for colonoscopies and CT colonography (CTC) is exceeding capacity in National Health Service Trusts.In many patients colonoscopies and CTCs show no significant bowel disease (SBD).Faecal Immunochemical Testing (FIT) is being introduced to prioritise patients for colonoscopies but is insufficient to identify non-SBD patients mean

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Cyclophilins and Their Roles in Hepatitis C Virus and Flavivirus Infections: Perspectives for Novel Antiviral Approaches

Cyclophilins are cellular peptidyl-prolyl isomerases that play an important role in viral infections, with demonstrated roles in the replication of hepatitis C virus (HCV) and other viruses in the Flaviviridae family, such as dengue virus Key Hanger (DENV) and yellow fever virus (YFV).Here, we discuss the roles of cyclophilins in HCV infection and

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